Reccomendations?

I have this idea for a story. It's a very vague idea based around the Rube Goldberg machine, or just a chain reaction kind of thing, but I have no idea what pairing to use. What (Whose Line) pairing would you want to see me write? I'm not discounting any particular pairings, but there are some that I know I wouldn't want to do, but I need to figure out the pairing before I figure out the way the story would work, and I just can't think of one. Or a time period. No idea.

And no, Kat, I'm not doing Jeff/Jeff/Jeff. :)